RIN1 Antibody | CSB-PA019726LA01HU

RIN1 Antibody | CSB-PA019726LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: RIN1

Aliases: Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1), RIN1

Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q13671

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Ras and Rab interactor 1 protein (192-341AA)

Immunogen Species: Human

Applications: ELISA, IF

Tested Applications: ELISA, IF; Recommended dilution: IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IF:1:50-1:200

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Signal transduction