Recombinant Rat Uteroglobin protein (Scgb1a1) (Active) | CSB-AP000221RA

Recombinant Rat Uteroglobin protein (Scgb1a1) (Active) | CSB-AP000221RA | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : Clara cell phospholipid-binding protein, Clara cells 10 kDa secretory protein, CC10, PCB-binding protein, Secretoglobin family 1A member 1

Gene Names: Scgb1a1,Cc10,Ugb,Utg

Research Areas: Immunology

Species: Rattus norvegicus (Rat)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 20-96aa

Sequence Info: SSDICPGFLQ VLEALLLGSE SNYEAALKPF NPASDLQNAG TQLKRLVDTL PQETRINIVK LTEKILTSPL CEQDLRV

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of ＞ 200 IU/m.

MW: 8.5 kDa

Purity: >97% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

PubMed ID: 2115524; 15489334; 2349092; 1560460; 7583672

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Secretoglobin family

Tissue Specificity: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways) .

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P17559

Uniprot Entry Name: UTER_RAT

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A