Recombinant Rat Type-2 angiotensin II receptor (Agtr2), partial | CSB-YP001466RA
- 25 - 35 Working Days
Recombinant Rat Type-2 angiotensin II receptor (Agtr2), partial | CSB-YP001466RA | Cusabio
Alternative Name(s): Angiotensin II type-2 receptor ;AT2
Gene Names: Agtr2
Research Areas: Others
Organism: Rattus norvegicus (Rat)
AA Sequence: MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLE
Tag Info: N-terminal 6xHis-tagged
Expression Region: 1-45aa
Sequence Info: Extracellular Domain
MW: 6.9 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation .
Reference: Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.Kambayashi Y., Bardhan S., Takahashi K., Tsuzuki S., Inui H., Hamakubo T., Inagami T.J. Biol. Chem. 268:24543-24546(1993)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity).
Involvement in disease:
Subcellular Location: Cell membrane, Multi-pass membrane protein
Protein Families: G-protein coupled receptor 1 family
Tissue Specificity: Abundant expression in fetal tissues, immature brain, skin wound and atretic ovarian follicles.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P35351
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A