Recombinant Rat Trophoblast glycoprotein (Tpbg), partial | CSB-EP024093RA
- 3 - 7 Working Days
Recombinant Rat Trophoblast glycoprotein (Tpbg), partial | CSB-EP024093RA | Cusabio
Alternative Name(s): 5T4 oncofetal trophoblast glycoprotein Short name: 5T4 oncotrophoblast glycoprotein Wnt-activated inhibitory factor 1 Short name: WAIF1
Gene Names: Tpbg
Research Areas: Others
Organism: Rattus norvegicus (Rat)
AA Sequence: SAPSSSLPSSSTSPAAFLASGSAQPPPAERCPAACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGNHLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQNGSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLTYASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEVVPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTS
Tag Info: N-terminal 6xHis-SUMO-tagged
Expression Region: 32-361aa
Sequence Info: Partial
MW: 51.8 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Reference: "Structure and expression of the rat 5T4 gene."Ninkina N.N., Buchman V.L.Submitted (MAY-1998)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Involvement in disease:
Subcellular Location: Cell membrane, Single-pass type I membrane protein
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q5PQV5
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A