Recombinant Rat MICOS complex subunit Mic60 (Immt), partial | CSB-CF665982RA

Recombinant Rat MICOS complex subunit Mic60 (Immt), partial | CSB-CF665982RA | Cusabio

Alternative Name(s): Mitochondrial inner membrane protein (Mitofilin) (Mic60)

Gene Names: Immt

Research Areas: Others

Organism: Rattus norvegicus (Rat)

AA Sequence: STSSSSGVTAGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPIQSGPLKISSVSEVMTDSELPMAQTQETNGDTPASAAGDPAPEVEHEDTINTECPNTDEGTSTFVTAALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAHAHRRIDQLNRELAQQKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIRVSCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLAGRVAMIDETKNSLYQ

Source: in vitro E.coli expression system

Tag Info: N-terminal 10xHis-tagged

Expression Region: 34-609aa

Sequence Info: Partial

MW: 66.3 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.

Reference: "Mitoproteome plasticity of rat brown adipocytes in response to cold acclimation." Navet R., Mathy G., Douette P., Dobson R.L., Leprince P., De Pauw E., Sluse-Goffart C., Sluse F.E. J. Proteome Res. 6:25-33(2007)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q3KR86

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A