Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial | CSB-YP009514RA1
- 3 - 7 Working Days
Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial | CSB-YP009514RA1 | Cusabio
Alternative Name(s): Glp1r; GlprGlucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R
Gene Names: Glp1r
Research Areas: Neuroscience
Organism: Rattus norvegicus (Rat)
AA Sequence: GPRPQGATVSLSETVQKWREYRHQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGIWLHKDNSSLPWRDLSECEESKQGERN
Tag Info: N-terminal 6xHis-tagged
Expression Region: 22-135aa
Sequence Info: Partial
MW: 15.1 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Reference: "Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1."Thorens B.Proc. Natl.Acad. Sci. U.S.A. 89:8641-8645(1992)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: G-protein coupled receptor for glucagon-like peptide 1 (GLP-1)
Involvement in disease:
Subcellular Location: Cell membrane, Multi-pass membrane protein
Protein Families: G-protein coupled receptor 2 family
Tissue Specificity: Pancreatic islets, stomach, lung, rat insulinoma cell line.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P32301
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A