Recombinant Rat C-X-C motif chemokine 2 protein (Cxcl2) (Active) | CSB-AP001401RA

Recombinant Rat C-X-C motif chemokine 2 protein (Cxcl2) (Active) | CSB-AP001401RA | Cusabio

Protein Description: Partial

Alternative Name (s) : Cytokine-induced neutrophil chemoattractant 3, Macrophage inflammatory protein 2, MIP2

Gene Names: Cxcl2,Cinc3,Mip-2,Mip2,Scyb2

Research Areas: Immunology

Species: Rattus norvegicus (Rat)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 28-100aa

Sequence Info: VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100 ng/ml.

MW: 7.9 kDa

Purity: >98% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation.

PubMed ID: 7665992; 7883948; 14624457; 1415488; 8043001; 8607872; 8471066

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Intercrine alpha (chemokine CxC) family

Tissue Specificity: At least expressed in the lung and trachea.

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P30348

Uniprot Entry Name: CXCL2_RAT

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A