Recombinant Phleum pratense Pollen allergen Phl p 1 (PHLPI) | CSB-EP331772EUQ

Recombinant Phleum pratense Pollen allergen Phl p 1 (PHLPI) | CSB-EP331772EUQ | Cusabio

Alternative Name(s): Allergen Phl p I Allergen: Phl p 1

Gene Names: PHLPI

Research Areas: Allergen

Organism: Phleum pratense (Common timothy)

AA Sequence: IPKVPPGPNITATYGDKWLDAKSTWYGKPTGAGPKDNGGACGYKDVDKPPFSGMTGCGNTPIFKSGRGCGSCFEIKCTKPEACSGEPVVVHITDDNEEPIAPYHFDLSGHAFGAMAKKGDEQKLRSAGELELQFRRVKCKYPEGTKVTFHVEKGSNPNYLALLVKYVNGDGDVVAVDIKEKGKDKWIELKESWGAIWRIDTPDKLTGPFTVRYTTEGGTKTEAEDVIPEGWKADTSYESK

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 24-263aa

Sequence Info: Full Length of Mature Protein

MW: 42.2 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance:

Reference: "Complementary DNA cloning of the major allergen Phl p I from timothy grass (Phleum pratense); recombinant Phl p I inhibits IgE binding to group I allergens from eight different grass species."Laffer S., Valenta R., Vrtala S., Susani M., van Ree R., Kraft D., Scheiner O., Duchene M.J. Allergy Clin. Immunol. 94:689-698(1994)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Expansin family, Expansin B subfamily

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P43213

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A