Recombinant Mouse Receptor-type tyrosine-protein phosphatase N2 (Ptprn2), partial | CSB-YP019060MO

Recombinant Mouse Receptor-type tyrosine-protein phosphatase N2 (Ptprn2), partial | CSB-YP019060MO | Cusabio

Alternative Name(s): PTP IA-2betaProtein tyrosine phosphatase-NP ;PTP-NP

Gene Names: Ptprn2

Research Areas: Others

Organism: Mus musculus (Mouse)

AA Sequence: RGRQLPGRLGCLFEDGLCGSLETCVNDGVFGRCQKVPVMDTYRYEVPPGALLHLKVTLQKLSRTGFTWQDDYTQRVIAQELANLPKAYLWHGEASGPARSLQQNADNEKWFSLEREVALAKTLRRYLPYLELLSQTPTANAHSRIDHETRPAKGEDSSPENILTYVAHTSALTYPPATRAKYPDNLLRPFSRLQPDELSPKVDGDIDKQKLIAALGAYTAQRLPGENDPEPRYLVHGSARAPRPFSATALSQRWPPPPGDAKDSPSMDDDTLLQSLLKDLQQNSEVDRLGPLKEEKADSVAGAIQSDPAEGSQESHGRGAEGQPREQTDAPETMLQDHRLSEVDDPVYKEVNRLSFQLGDLLKDYGSPLLPEGPLLEKSSREEIKKSEQPEEVLSSEEETAGVEHVRSRTYSKDLFERKPNSEPQPRRLEDQFQNRAPELWEDEESLKLAAQGPPSGGLQLEVQPSEEQQGYILTGNNPLSPEKGKQLMDQVAHILRVPSSFFADIKVLGPAVTFKVSANIQNMTTADVIKAAADNKDQLEKATGLTILQSGIRPKGKLKLLPHQEEQEDSTK

Source: Yeast

Tag Info: N-terminal 6xHis-tagged

Expression Region: 28-600aa

Sequence Info: Extracellular Domain

MW: 65.7 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Implicated in development of nervous syst and pancreatic endocrine cells.

Reference: PTP-NP, a new member of the receptor protein tyrosine phosphatase family, implicated in development of nervous system and pancreatic endocrine cells.Chiang M.-K., Flanagan J.G.Development 122:2239-2250(1996)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Plays a role in vesicle-mediated secretory processes

Involvement in disease:

Subcellular Location: Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type I membrane protein, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass type I membrane protein

Protein Families: Protein-tyrosine phosphatase family

Tissue Specificity: Detected in brain (PubMed:15220191, PubMed:19361477). Detected in pancreas islets (at protein level) (PubMed:8681804). Detected in pancreas and brain (PubMed:8681804, PubMed:8637868).

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P80560

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A