Cusabio Mouse Recombinants
Recombinant Mouse Plexin domain-containing protein 1 (Plxdc1), partial | CSB-YP838718MO
- 3 - 7 Working Days
Recombinant Mouse Plexin domain-containing protein 1 (Plxdc1), partial | CSB-YP838718MO | Cusabio
Alternative Name(s): Tumor endothelial marker 7
Gene Names: Plxdc1
Research Areas: Cardiovascular
Organism: Mus musculus (Mouse)
AA Sequence: LSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGT
Tag Info: N-terminal 6xHis-tagged
Expression Region: 20-426aa
Sequence Info: Extracellular Domain
MW: 47.3 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Plays a critical role in endothelial cell capillary morphogenesis.
Reference: "Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R." Nanda A., Buckhaults P., Seaman S., Agrawal N., Boutin P., Shankara S., Nacht M., Teicher B., Stampfl J., Singh S., Vogelstein B., Kinzler K.W., St Croix B. Cancer Res. 64:8507-8511(2004)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Plays a critical role in endothelial cell capillary morphogenesis.
Involvement in disease:
Subcellular Location: Cell membrane, Single-pass type I membrane protein, Cell junction, tight junction
Protein Families: Plexin family
Tissue Specificity: Detected in brain. Highly expressed in Purkinje cells of the cerebellum.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q91ZV7
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A