Recombinant Mouse Microtubule-associated protein 2 (Map2), partial | CSB-EP013408MO

Recombinant Mouse Microtubule-associated protein 2 (Map2), partial | CSB-EP013408MO | Cusabio

Alternative Name(s): Map2; Mtap2; Microtubule-associated protein 2; MAP-2

Gene Names: Map2

Research Areas: Others

Organism: Mus musculus (Mouse)

AA Sequence: GMEGEKLPPVPFAQTFGTNLEDRKQSTEPSIVMPSIGLSAEPPAPKEPKDWFIEMPTESKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGSFTLPLDTMKNERVSEGPRPFAPVFFQSDDKVSLQDPSALATSKESSKDEEPLKDKADKVADVSISEVTTLLGNVHSPVVEGYVGENISGEVKVTTDQEKKETSAPSVQEPTLTETEPQTKLDEKSTVSIEEAVAKKEESFKLRDDKTGVIQTSTEQSFSKEDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQGLFEEKTADKNKLEGAGSATIAEVEMP

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 213-559aa

Sequence Info: Partial

MW: 54 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also se to have a stiffening effect on microtubules.

Reference: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M.Mol. Cell. Proteomics 6:283-293(2007)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Involvement in disease:

Subcellular Location: Cytoplasm, cytoskeleton, Cell projection, dendrite

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P20357

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A