Recombinant Mouse Interleukin-7 receptor subunit alpha (Il7r), partial | CSB-EP011670MO

Recombinant Mouse Interleukin-7 receptor subunit alpha (Il7r), partial | CSB-EP011670MO | Cusabio

Alternative Name(s): Short name: IL-7 receptor subunit alpha Short name: IL-7R subunit alpha Short name: IL-7R-alpha Short name: IL-7RA

Gene Names: Il7r

Research Areas: Immunology

Organism: Mus musculus (Mouse)

AA Sequence: ESGNAQDGDLEDADADDHSFWCHSQLEVDGSQHLLTCAFNDSDINTANLEFQICGALLRVKCLTLNKLQDIYFIKTSEFLLIGSSNICVKLGQKNLTCKNMAINTIVKAEAPSDLKVVYRKEANDFLVTFNAPHLKKKYLKKVKHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPSSTFETPEPKNQGGWD

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 21-239aa

Sequence Info: Extracellular Domain

MW: 41 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Reference: "Structural basis of the proinflammatory signaling complex mediated by TSLP."Verstraete K., van Schie L., Vyncke L., Bloch Y., Tavernier J., Pauwels E., Peelman F., Savvides S.N.Nat. Struct. Mol. Biol. 21:375-382(2014)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Involvement in disease:

Subcellular Location: Membrane, Single-pass type I membrane protein

Protein Families: Type I cytokine receptor family, Type 4 subfamily

Tissue Specificity: Spleen, thymus and fetal liver.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P16872

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A