Cusabio Mouse Recombinants
Recombinant Mouse Immunoglobulin J chain (Igj) | CSB-YP011337MO
- SKU:
- CSB-YP011337MO
- Availability:
- 3 - 7 Working Days
Description
Recombinant Mouse Immunoglobulin J chain (Igj) | CSB-YP011337MO | Cusabio
Alternative Name(s): Jchain; IgjImmunoglobulin J chain
Gene Names: Jchain
Research Areas: Immunology
Organism: Mus musculus (Mouse)
AA Sequence: GDDEATILADNKCMCTRVTSRIIPSTEDPNEDIVERNIRIVVPLNNRENISDPTSPLRRNFVYHLSDVCKKCDPVEVELEDQVVTATQSNICNEDDGVPETCYMYDRNKCYTTMVPLRYHGETKMVQAALTPDSCYPD
Source: Yeast
Tag Info: N-terminal 6xHis-tagged
Expression Region: 22-159aa
Sequence Info: Full Length of Mature Protein
MW: 17.7 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Reference: "Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells." Randall T.D., Brewer J.W., Corley R.B. J. Biol. Chem. 267:18002-18007(1992)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Involvement in disease:
Subcellular Location: Secreted
Protein Families:
Tissue Specificity:
Paythway:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P01592
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A