Recombinant Mouse Cathepsin G (Ctsg) | CSB-EP006190MO

Recombinant Mouse Cathepsin G (Ctsg) | CSB-EP006190MO | Cusabio

Alternative Name(s): Vimentin-specific protease ;VSP

Gene Names: Ctsg

Research Areas: Others

Organism: Mus musculus (Mouse)

AA Sequence: IIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 21-261aa

Sequence Info: Full Length of Mature Protein

MW: 42.9 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movent and mitosis.

Reference: Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene.Heusel J.W., Scarpati E.M., Jenkins N.A., Gilbert D.J., Copeland N.G., Shapiro S.D., Ley T.J.Blood 81:1614-1623(1993)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis.

Involvement in disease:

Subcellular Location: Membrane

Protein Families: Peptidase S1 family

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P28293

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A