Recombinant Mouse C-C motif chemokine 28 protein (Ccl28) (Active) | CSB-AP001081MO

Recombinant Mouse C-C motif chemokine 28 protein (Ccl28) (Active) | CSB-AP001081MO | Cusabio

Protein Description: Partial

Alternative Name (s) : Small-inducible cytokine A28,

Gene Names: Ccl28,Scya28

Research Areas: Immunology

Species: Mus musculus (Mouse)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 20-130aa

Sequence Info: SEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS R

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration range of 1.0-10.0 ng/ml.

MW: 12.6 kDa

Purity: >97% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Chemotactic for resting CD4, CD8 T-cells and eosinophils (By similarity) . Binds to CCR10 and induces calcium mobilization in a dose-dependent manner. {ECO:0000250}.

PubMed ID: 10781587; 15489334

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Chemotactic for resting CD4, CD8 T-cells and eosinophils (By similarity) . Binds to CCR10 and induces calcium mobilization in a dose-dependent manner.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Intercrine beta (chemokine CC) family

Tissue Specificity: Mainly expressed in testis, epithelial cells of normal colon, kidney, Peyer patches, lymph nodes. Also found in lower levels in brain, spleen and lung.

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9JIL2

Uniprot Entry Name: CCL28_MOUSE

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A