Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial (Alas2) | CSB-EP001560MO

Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial (Alas2) | CSB-EP001560MO | Cusabio

Alternative Name(s): 5-aminolevulinic acid synthase 2 (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2) (ALAS-E)

Gene Names: Alas2

Research Areas: Cancer

Organism: Mus musculus (Mouse)

AA Sequence: QIHLKATKAGGDSPSWAKSHCPFMLSELQDRKSKIVQRAAPEVQEDVKTFKTDLLSTMDSTTRSHSFPSFQEPEQTEGAVPHLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMASKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGERDGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLPLQDVSVAACNFCHRPVHFELMSEWERSYFGNMGPQYVTTYA

Source: E.coli

Tag Info: N-terminal 6xHis-tagged

Expression Region: 50-587aa

Sequence Info: Full Length of Mature Protein

MW: 65.6 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: There are two delta-ALA synthases in vertebrates: an erythroid- specific form and one which is expressed in all tissues.

Reference: "The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase." Goodfellow B.J., Dias J.S., Ferreira G.C., Henklein P., Wray V., Macedo A.L. FEBS Lett. 505:325-331(2001)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P08680

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A