Cusabio Active Proteins
Recombinant Human Ubiquitin-associated domain-containing protein 1 (UBAC1) (Active) | CSB-EP887116HU
- SKU:
- CSB-EP887116HU
- Availability:
- 13 to 23 Working Days
Description
Recombinant Human Ubiquitin-associated domain-containing protein 1 (UBAC1) (Active) | CSB-EP887116HU | Cusabio
Protein Description: Full Length
Alternative Name (s) : E3 ubiquitin-protein ligase subunit KPC2 (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2) (UBA domain-containing protein 1) (GBDR1) (KPC2) (UBADC1)
Gene Names: UBAC1
Research Areas: Cell Biology
Species: Homo sapiens (Human)
Source: E.coli
Tag Info: N-terminal GST-tagged
Expression Region: 1-405aa
Sequence Info: MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT
Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized CCL5 at 2 μg/ml can bind human UBAC1, the EC50 of human UBAC1 protein is 86.67-97.25 μg/ml.
MW: 72.3 kDa
Purity: Greater than 85% as determined by SDS-PAGE.
Endotoxin: Not test.
Relevance: Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
PubMed ID:
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function:
Involvement in disease:
Subcellular Location:
Protein Families:
Tissue Specificity:
Paythway:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q9BSL1
Uniprot Entry Name:
HGNC Database Link: N/A
UniGene Database Link: N/A
KEGG Database Link: N/A
STRING Database Link: N/A
OMIM Database Link: N/A