Recombinant Human Transforming growth factor beta-3 (TGFB3), partial | CSB-EP023449HU

Recombinant Human Transforming growth factor beta-3 (TGFB3), partial | CSB-EP023449HU | Cusabio

Alternative Name(s): Cleaved into the following chain: Latency-associated peptide Short name: LAP

Gene Names: TGFB3

Research Areas: Cancer

Organism: Homo sapiens (Human)

AA Sequence: LSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 24-300aa

Sequence Info: Partial

MW: 48.1 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Involved in embryogenesis and cell differentiation.

Reference: "Identification of another member of the transforming growth factor type beta gene family."ten Dijke P., Hansen P., Iwata K., Pieler C., Foulkes J.G.Proc. Natl. Acad. Sci. U.S.A. 85:4715-4719(1988)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Involved in embryogenesis and cell differentiation.

Involvement in disease: Arrhythmogenic right ventricular dysplasia, familial, 1 (ARVD1); Loeys-Dietz syndrome 5 (LDS5)

Subcellular Location: Secreted

Protein Families: TGF-beta family

Tissue Specificity:

Paythway: Hipposignalingpathway

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P10600

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM