Recombinant Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4), partial | CSB-MP850304HU

Recombinant Human T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4), partial | CSB-MP850304HU | Cusabio

Alternative Name(s): T-cell immunoglobulin mucin receptor 4 (TIM-4) (T-cell membrane protein 4)

Gene Names: TIMD4

Research Areas: Immunology

Organism: Homo sapiens (Human)

AA Sequence: ETVVTEVLGHRVTLPCLYSSWSHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGWFNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTTGTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSSVESTSADTVLLTSKESKVWDLPSTSHVSMWKTSDSVSSPQPGASDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQ

Source: Mammalian cell

Tag Info: C-terminal hFc-tagged

Expression Region: 25-314aa

Sequence Info: Partial

MW: 60.3

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.

Reference: "Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis." Page N.S., Jones G., Stewart G.J. Int. Arch. Allergy Immunol. 141:331-336(2006)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q96H15

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A