Recombinant Human Syndecan-4 (SDC4), partial (Active) | CSB-AP000331HU
- 5 to 10 Working Days
Recombinant Human Syndecan-4 (SDC4) ,partial (Active) | CSB-AP000331HU | Cusabio
Protein Description: Partial
Alternative Name (s) : SYND4, Ryudocan core protein
Gene Names: SDC4
Research Areas: Signal Transduction
Species: Homo sapiens (Human)
Tag Info: Tag-Free
Expression Region: 19-145aa
Sequence Info: ESIRETEVID PQDLLEGRYF SGALPDDEDV VGPGQESDDF ELSGSGDLDD LEDSMIGPEV VHPLVPLDNH IPERAGSGSQ VPTEPKKLEE NEVIPKRISP VEESEDVSNK VSMSSTVQGS NIFERTE
Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by binding ability in a functional ELISA. Immobilized rHuSYND4 at 500 ng/ml (100 μl/well) can bind rHubFGF with a linear range of 0.1-10 ng/ml.
MW: 13.9 kDa
Purity: >95% as determined by SDS-PAGE and HPLC.
Endotoxin: Less than 1.0 EU/µg as determined by LAL method.
Relevance: Cell surface proteoglycan that bears heparan sulfate.
PubMed ID: 1500433; 7916598; 8797100; 14702039; 11780052; 15489334; 8889549; 9169435; 14675776; 16007225; 21269460; 24275569; 11456484; 12842047; 16533050
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function: Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP
Involvement in disease:
Subcellular Location: Isoform 1: Membrane, Single-pass type I membrane protein, Secreted
Protein Families: Syndecan proteoglycan family
Tissue Specificity: Expressed in epithelial and fibroblastic cells.
Form: Lyophilized powder
Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P31431
Uniprot Entry Name: SDC4_HUMAN
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM