Recombinant Human Syndecan-4 (SDC4), partial (Active) | CSB-AP000331HU

Recombinant Human Syndecan-4 (SDC4) ,partial (Active) | CSB-AP000331HU | Cusabio

Protein Description: Partial

Alternative Name (s) : SYND4, Ryudocan core protein

Gene Names: SDC4

Research Areas: Signal Transduction

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 19-145aa

Sequence Info: ESIRETEVID PQDLLEGRYF SGALPDDEDV VGPGQESDDF ELSGSGDLDD LEDSMIGPEV VHPLVPLDNH IPERAGSGSQ VPTEPKKLEE NEVIPKRISP VEESEDVSNK VSMSSTVQGS NIFERTE

Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by binding ability in a functional ELISA. Immobilized rHuSYND4 at 500 ng/ml (100 μl/well) can bind rHubFGF with a linear range of 0.1-10 ng/ml.

MW: 13.9 kDa

Purity: >95% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Cell surface proteoglycan that bears heparan sulfate.

PubMed ID: 1500433; 7916598; 8797100; 14702039; 11780052; 15489334; 8889549; 9169435; 14675776; 16007225; 21269460; 24275569; 11456484; 12842047; 16533050

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP

Involvement in disease:

Subcellular Location: Isoform 1: Membrane, Single-pass type I membrane protein, Secreted

Protein Families: Syndecan proteoglycan family

Tissue Specificity: Expressed in epithelial and fibroblastic cells.

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P31431

Uniprot Entry Name: SDC4_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM