Recombinant Human Serpin B4 (SERPINB4) | CSB-EP021072HU

Recombinant Human Serpin B4 (SERPINB4) | CSB-EP021072HU | Cusabio

Alternative Name(s): Leupin Peptidase inhibitor 11 Short name: PI-11 Squamous cell carcinoma antigen 2 Short name: SCCA-2

Gene Names: SERPINB4

Research Areas: Cancer

Organism: Homo sapiens (Human)

AA Sequence: MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 1-390aa

Sequence Info: Full Length

MW: 60.9 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: May act as a protease inhibitor to modulate the host immune response against tumor cells.

Reference: "Identification of a novel human serpin gene; cloning sequencing and expression of leupin."Barnes R.C., Worrall D.M.FEBS Lett. 373:61-65(1995)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: May act as a protease inhibitor to modulate the host immune response against tumor cells.

Involvement in disease:

Subcellular Location: Cytoplasm

Protein Families: Serpin family, Ov-serpin subfamily

Tissue Specificity: Squamous cells.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P48594

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM