Recombinant Human Putative teratocarcinoma-derived growth factor 3 (TDGF1P3) | CSB-MP344744HU

Recombinant Human Putative teratocarcinoma-derived growth factor 3 (TDGF1P3) | CSB-MP344744HU | Cusabio

Alternative Name(s): Cripto-3 growth factor (Epidermal growth factor-like cripto protein CR3) (Teratocarcinoma-derived growth factor 1 pseudogene 3) (CRIPTO3) (TDGF2) (TDGF3)

Gene Names: TDGF1P3

Research Areas: Others

Organism: Homo sapiens (Human)

AA Sequence: LGHQEFARPSRGDLAFRDDSIWPQEEPAIRPRSSQRVLPMGIQHSKELNRTCCLNGGTCMLESFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLAGICLSIQSYY

Source: Mammalian cell

Tag Info: C-terminal 6xHis-tagged

Expression Region: 31-188aa

Sequence Info: Full Length of Mature Protein

MW: 20

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

Reference: "Truncated activin type I receptor Alk4 isoforms are dominant negative receptors inhibiting activin signaling." Zhou Y., Sun H., Danila D.C., Johnson S.R., Sigai D.P., Zhang X., Klibanski A. Mol. Endocrinol. 14:2066-2075(2000)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P51864

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A