Recombinant Human Pro-neuregulin-1, membrane-bound isoform (NRG1), partial | CSB-EP016077HU1

Recombinant Human Pro-neuregulin-1, membrane-bound isoform (NRG1), partial | CSB-EP016077HU1 | Cusabio

Alternative Name(s): Neuregulin 1

Gene Names: NRG1

Research Areas: Neuroscience

Organism: Homo sapiens (Human)

AA Sequence: NELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGT

Source: E.coli

Tag Info: N-terminal 6xHis-GST-tagged

Expression Region: 75-176aa

Sequence Info: Partial

MW: 42.2 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance:

Reference: "Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway." Tsai P.W., Shiah S.G., Lin M.T., Wu C.W., Kuo M.L. J Biol Chem 278:5750-5759(2003)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q02297

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A