Recombinant Human Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) | CSB-EP880077HU

Recombinant Human Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) | CSB-EP880077HU | Cusabio

Alternative Name(s): DJ858B16; dJ858B16.2; DKFZp566G2246; Phosphatidylserine decarboxylase; Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase proenzyme; PISD; PISD_HUMAN; PSD; PSDC; PSSC

Gene Names: PISD

Research Areas: Metabolism

Organism: Homo sapiens (Human)

AA Sequence: MMCQSEARQGPELRAAKWLHFPQLALRRRLGQLSCMSRPALKLRSWPLTVLYYLLPFGALRPLSRVGWRPVSRVALYKSVPTRLLSRAWGRLNQVELPHWLRRPVYSLYIWTFGVNMKEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGRILNFGQVKNCEVEQVKGVTYSLESFLGPRMCTEDLPFPPAASCDSFKNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIYFDRDLHTNSPRHSKGSYNDFSFVTHTNREGVPMRKGEHLGEFNLGSTIVLIFEAPKDFNFQLKTGQKIRFGEALGSL

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 1-375aa

Sequence Info: Full Length of Isoform 2

MW: 59 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance:

Reference: A genome annotation-driven approach to cloning the human ORFeome.Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I.Genome Biol. 5:R84.1-R84.11(2004)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.

Involvement in disease:

Subcellular Location: Phosphatidylserine decarboxylase beta chain: Mitochondrion inner membrane, Single-pass membrane protein, Intermembrane side, SUBCELLULAR LOCATION: Phosphatidylserine decarboxylase alpha chain: Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side

Protein Families: Phosphatidylserine decarboxylase family, PSD-B subfamily, Eukaryotic type I sub-subfamily

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9UG56

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM