Recombinant Human Paired box protein Pax-2 (PAX2), partial | CSB-RP115644h

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CSB-RP115644h
Availability:
13 - 23 Working Days
  • Recombinant Human Paired box protein Pax-2 (PAX2), partial
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
£196.00 - £1,021.60

Description

Recombinant Human Paired box protein Pax-2 (PAX2), partial | CSB-RP115644h | Cusabio

Alternative Name(s): PAX2; Paired box protein Pax-2

Gene Names: PAX2

Research Areas: Developmental Biology

Organism: Homo sapiens (Human)

AA Sequence: MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYP

Source: E.coli

Tag Info: N-terminal GST-tagged

Expression Region: 1-388aa

Sequence Info: Partial of Isoform 4

MW: 68.2 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Transcription factor that may have a role in kidney cell differentiation . Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Reference: Genomic structure of the human PAX2 gene.Sanyanusin P., Norrish J.H., Ward T.A., Nebel A., McNoe L.A., Eccles M.R.Genomics 35:258-261(1996)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Transcription factor that may have a role in kidney cell differentiation

Involvement in disease: Papillorenal syndrome (PAPRS); Focal segmental glomerulosclerosis 7 (FSGS7)

Subcellular Location: Nucleus

Protein Families:

Tissue Specificity: Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q02962

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM

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