Recombinant Human Orofacial cleft 1 candidate gene 1 protein (OFCC1), partial | CSB-EP809031HU

Recombinant Human Orofacial cleft 1 candidate gene 1 protein (OFCC1), partial | CSB-EP809031HU | Cusabio

Alternative Name(s): Orofacial clefting chromosomal breakpoint region candidate 1 protein

Gene Names: OFCC1

Research Areas: Epigenetics and Nuclear Signaling

Organism: Homo sapiens (Human)

AA Sequence: REKFQQKALKQTKQKKSKSAEFLMVKEDREATEGTGNPAFNMSSPDLSACQTAEKKVIRHDMPDRTLAAHQQKFRLPASAEPKGNEYGRNYFDPLMDEEINPRQCATEVSREDDDRIFYNRLTKLFDESRQGEPQDESGREETLNSEAPGSSNKSHEIHKEASEATTAHLEEFQRSQKTIILLGSSPLEQEIRSTSLHCMEDEMSHPWILLLKVTAVIRSRRYYREQRF

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 3-231aa

Sequence Info: Partial

MW: 42.5 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance:

Reference: "Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region."Davies S.J., Wise C., Venkatesh B., Mirza G., Jefferson A., Volpi E.V., Ragoussis J.Cytogenet. Genome Res. 105:47-53(2004)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease: A chromosomal aberration involving OFCC1 is found in patients with orofacial cleft.

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q8IZS5

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: N/A

STRING Database Link: STRING

OMIM Database Link: OMIM