Recombinant Human Monocarboxylate transporter 5 (SLC16A4), partial | CSB-EP021411HU

Recombinant Human Monocarboxylate transporter 5 (SLC16A4), partial | CSB-EP021411HU | Cusabio

Alternative Name(s): Monocarboxylate transporter 4 Solute carrier family 16 member 4

Gene Names: SLC16A4

Research Areas: Metabolism

Organism: Homo sapiens (Human)

AA Sequence: RPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNP

Source: E.coli

Tag Info: N-terminal 10xHis-tagged

Expression Region: 196–299aa

Sequence Info: Partial

MW: 17.7 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).

Reference: "Effects of strength training on muscle lactate release and MCT1 and MCT4 content in healthy and type 2 diabetic humans." Juel C., Holten M.K., Dela F. J. Physiol. (Lond.) 556:297-304(2004)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: O15374

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A