Cusabio Human Recombinants
Recombinant Human Metalloreductase STEAP1 (STEAP1), partial | CSB-RP133544h
- SKU:
- CSB-RP133544h
- Availability:
- 13 - 23 Working Days
Description
Recombinant Human Metalloreductase STEAP1 (STEAP1), partial | CSB-RP133544h | Cusabio
Alternative Name(s): Six-transmembrane epithelial antigen of prostate 1
Gene Names: STEAP1
Research Areas: Transport
Organism: Homo sapiens (Human)
AA Sequence: SRKDITNQEELWKMKPRRNLEEDDYLHKDTGETSMLKRPVLLHLHQTAHADEFDCPSELQHTQELFP
Source: E.coli
Tag Info: N-terminal GST-tagged
Expression Region: 3-69aa
Sequence Info: Partial
MW: 35 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor .
Reference: The Steap proteins are metalloreductases.Ohgami R.S., Campagna D.R., McDonald A., Fleming M.D.Blood 108:1388-1394(2006)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Involvement in disease:
Subcellular Location: Endosome membrane, Multi-pass membrane protein
Protein Families: STEAP family
Tissue Specificity: Ubiquitously expressed. Highly expressed in prostate tumors.
Paythway:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q9UHE8
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM