Recombinant Human Interleukin-22 protein (IL22) (Active) | CSB-AP001891HU

Recombinant Human Interleukin-22 protein (IL22) (Active) | CSB-AP001891HU | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : IL-22, IL-10-related T-cell-derived-inducible factor, IL-TIF

Gene Names: IL22,ILTIF,ZCYTO18,UNQ3099/PRO10096

Research Areas: Immunology

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 34-179aa

Sequence Info: M+APISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.3 ng/ml, corresponding to a specific activity of ＞ 3.3 × 106 IU/mg.

MW: 16.9 kDa

Purity: >97% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Cytokine that contributes to the inflammatory response in vivo.

PubMed ID: 10954742; 11197690; 10875937; 12975309; 15489334; 15340161; 11856845; 15983417; 18599299

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Cytokine that contributes to the inflammatory response in vivo.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: IL-10 family

Tissue Specificity:

Paythway: Jak-STATsignalingpathway

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 5.0

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9GZX6

Uniprot Entry Name: IL22_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM