Recombinant Human Guanine nucleotide-binding protein subunit alpha-15 (GNA15) | CSB-EP009587HU

Recombinant Human Guanine nucleotide-binding protein subunit alpha-15 (GNA15) | CSB-EP009587HU | Cusabio

Alternative Name(s): Epididymis tissue protein Li 17E Guanine nucleotide-binding protein subunit alpha-16

Gene Names: GNA15

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL

Source: E.coli

Tag Info: N-terminal 6xHis-Trx-tagged

Expression Region: 1-374aa

Sequence Info: Full Length

MW: 60.6 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Reference: "G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells." Amatruda T.T. III, Steele D.A., Slepak V.Z., Simon M.I. Proc. Natl. Acad. Sci. U.S.A. 88:5587-5591(1991)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Involvement in disease:

Subcellular Location:

Protein Families: G-alpha family, G(q) subfamily

Tissue Specificity: Specifically expressed in hematopoietic cells. Expressed in epididymis (at protein level).

Paythway: Calciumsignalingpathway

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P30679

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM