Recombinant Human Fructose-bisphosphate aldolase A (ALDOA) | CSB-EP001583HU

Recombinant Human Fructose-bisphosphate aldolase A (ALDOA) | CSB-EP001583HU | Cusabio

Alternative Name(s): Lung cancer antigen NY-LU-1Muscle-type aldolase

Gene Names: ALDOA

Research Areas: Metabolism

Organism: Homo sapiens (Human)

AA Sequence: PYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY

Source: E.coli

Tag Info: N-terminal GST-tagged

Expression Region: 2-364aa

Sequence Info: Full Length of Mature Protein

MW: 66.3 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein .

Reference: Nucleotide sequence of a cDNA clone for human aldolase a messenger RNA in the liver.Sakakibara M., Mukai T., Hori K.Biochem. Biophys. Res. Commun. 131:413-420(1985)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).

Involvement in disease: Glycogen storage disease 12 (GSD12)

Subcellular Location: Cytoplasm, myofibril, sarcomere, I band, Cytoplasm, myofibril, sarcomere, M line

Protein Families: Class I fructose-bisphosphate aldolase family

Tissue Specificity:

Paythway: HIF-1signalingpathway

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P04075

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM