Cusabio Active Proteins
Recombinant Human Endothelin receptor type B (EDNRB) (Active) | CSB-CF007404HU
- 18 to 23 Working Days
Recombinant Human Endothelin receptor type B (EDNRB) (Active) | CSB-CF007404HU | Cusabio
Protein Description: Full Length
Alternative Name (s) : Endothelin receptor non-selective type
Gene Names: EDNRB
Research Areas: Signal Transduction
Species: Homo sapiens (Human)
Source: in vitro E.coli expression system
Tag Info: C-terminal 10xHis-tagged
Expression Region: 27-442aa
Sequence Info: EERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized EDNRB at 5 μg/ml can bind human EDN1 with a linear range of 6.25-25.00 μg/ml.
MW: 50.3 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Endotoxin: Not test.
Relevance: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Involvement in disease:
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P24530
Uniprot Entry Name:
HGNC Database Link: N/A
UniGene Database Link: N/A
KEGG Database Link: N/A
STRING Database Link: N/A
OMIM Database Link: N/A