Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) | CSB-BP884430HU

Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) | CSB-BP884430HU | Cusabio

Alternative Name(s): Cysteine-rich secretory protein 11 Short name: CRISP-11 LCCL domain-containing cysteine-rich secretory protein 2 CRISP11, LCRISP2

Gene Names: CRISPLD2

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: YLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFVKSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDEPSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSESLGTPRDGKAFRIFAVRQ

Source: Baculovirus

Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-tagged

Expression Region: 23-497aa

Sequence Info: Full Length of Mature Protein

MW: 97.8 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Promotes matrix assembly.

Reference: "The novel lipopolysaccharide-binding protein CRISPLD2 is a critical serum protein to regulate endotoxin function." Wang Z.Q., Xing W.M., Fan H.H., Wang K.S., Zhang H.K., Wang Q.W., Qi J., Yang H.M., Yang J., Ren Y.N., Cui S.J., Zhang X., Liu F., Lin D.H., Wang W.H., Hoffmann M.K., Han Z.G. J. Immunol. 183:6646-6656(2009)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Promotes matrix assembly.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: CRISP family

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9H0B8

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM