Recombinant Human Collagen alpha-1 (XV) chain (COL15A1), partial | CSB-EP005722HU

Recombinant Human Collagen alpha-1 (XV) chain (COL15A1), partial | CSB-EP005722HU | Cusabio

Alternative Name(s): Collagen alpha-1(XV) chain [Cleaved into: Restin(Endostatin-XV)(Related to endostatin)(Restin-I); Restin-2(Restin-II); Restin-3(Restin-III); Restin-4(Restin-IV)]

Gene Names: COL15A1

Research Areas: Cancer

Organism: Homo sapiens (Human)

AA Sequence: HLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDP

Source: E.coli

Tag Info: N-terminal 10xHis-tagged

Expression Region: 40-228aa

Sequence Info: Partial

MW: 26.5 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.; Restin potently inhibits angiogenesis.

Reference: "Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin." Ramchandran R., Dhanabal M., Volk R., Waterman M.J.F., Segal M., Lu H., Knebelmann B., Sukhatme V.P. Biochem. Biophys. Res. Commun. 255:735-739(1999)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function:

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P39059

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A