Recombinant Human Cellular nucleic acid-binding protein (CNBP) | CSB-EP005637HU

Recombinant Human Cellular nucleic acid-binding protein (CNBP) | CSB-EP005637HU | Cusabio

Alternative Name(s): Zinc finger protein 9

Gene Names: CNBP

Research Areas: Epigenetics and Nuclear Signaling

Organism: Homo sapiens (Human)

AA Sequence: SSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 2-170aa

Sequence Info: Full Length of Isoform 2

MW: 34.6 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Single-stranded DNA-binding protein, with specificity to the sterol regulatory elent (SRE). Involved in sterol-mediated repression.

Reference: Identification of a zinc finger protein that binds to the sterol regulatory element.Rajavashisth T.B., Taylor A.K., Andalibi A., Svenson K.L., Lusis A.J.Science 245:640-643(1989)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.

Involvement in disease: Dystrophia myotonica 2 (DM2)

Subcellular Location: Cytoplasm, Endoplasmic reticulum

Protein Families:

Tissue Specificity: Present in all tissues examined.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P62633

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM