Recombinant Human Baculoviral IAP repeat-containing protein 8 (BIRC8) | CSB-EP846680HU

Recombinant Human Baculoviral IAP repeat-containing protein 8 (BIRC8) | CSB-EP846680HU | Cusabio

Alternative Name(s): Inhibitor of apoptosis-like protein 2

Gene Names: BIRC8

Research Areas: Cell Biology

Organism: Homo sapiens (Human)

AA Sequence: MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLGVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSMVIDFKQRVFMS

Source: E.coli

Tag Info: N-terminal GST-tagged

Expression Region: 1-236aa

Sequence Info: Full Length of BC039318

MW: 54.1 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Protects against apoptosis mediated by BAX.

Reference: "Genomic organization of the X-linked inhibitor of apoptosis and identification of a novel testis-specific transcript." Lagace M., Xuan J.-Y., Young S.S., McRoberts C., Maier J., Rajcan-Separovic E., Korneluk R.G. Genomics 77:181-188(2001)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Protects against apoptosis mediated by BAX.

Involvement in disease:

Subcellular Location: Cytoplasm

Protein Families: IAP family

Tissue Specificity: Testis specific in normal tissues.

Paythway: Ubiquitinmediatedproteolysis

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q96P09

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A