Recombinant Human Annexin A9 (ANXA9), partial | CSB-EP001852HU

Recombinant Human Annexin A9 (ANXA9), partial | CSB-EP001852HU | Cusabio

Alternative Name(s): Annexin XXXI;Annexin-31;Annexin-9;Pemphaxin

Gene Names: ANXA9

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: MAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRAEGPSREETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAEDM

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 8-345aa

Sequence Info: Partial

MW: 53.7 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Low affinity receptor for acetylcholine known to be targeted by disease-causing pphigus vulgaris antibodies in keratinocytes.

Reference: Expression profile and structural divergence of novel human annexin 31.Morgan R.O., Fernandez M.-P.FEBS Lett. 434:300-304(1998)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

Involvement in disease:

Subcellular Location:

Protein Families: Annexin family

Tissue Specificity: Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: O76027

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM