Recombinant Human 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) | CSB-YP801815HU
- 3 - 7 Working Days
Recombinant Human 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) | CSB-YP801815HU | Cusabio
Alternative Name(s): Short chain dehydrogenase/reductase family 16C member 3 (Short-chain dehydrogenase/reductase 9 ) (17-beta-HSD 13) (SCDR9) (SDR16C3)
Gene Names: HSD17B13
Research Areas: Others
Organism: Homo sapiens (Human)
AA Sequence: ESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK
Tag Info: N-terminal 6xHis-tagged and C-terminal Myc-tagged
Expression Region: 20-300aa
Sequence Info: Full Length of Mature Protein of Isoform 2
MW: 34.8 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Reference: "Comparative proteomic study reveals 17beta-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease." Su W., Wang Y., Jia X., Wu W., Li L., Tian X., Li S., Wang C., Xu H., Cao J., Han Q., Xu S., Chen Y., Zhong Y., Zhang X., Liu P., Gustafsson J.A., Guan Y. Proc. Natl. Acad. Sci. U.S.A. 111:11437-11442(2014)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Involvement in disease:
Subcellular Location: Secreted
Protein Families: Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity: Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q7Z5P4
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM