Recombinant Dog Serum amyloid A protein (SAA1) | CSB-EP020656DO
- 3 - 7 Working Days
Recombinant Dog Serum amyloid A protein (SAA1) | CSB-EP020656DO | Cusabio
Alternative Name(s): Amyloid fibril protein AA
Gene Names: SAA1
Research Areas: Others
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
AA Sequence: QWYSFVSEAAQGAWDMWRAYSDMREANYKNSDKYFHARGNYDAAQRGPGGAWAAKVISDARENSQRITDLLRFGDSGHGAEDSKADQAANEWGRSGKDPNHFRPAGLPDKY
Tag Info: N-terminal 6xHis-GST-tagged
Expression Region: 19-129aa
Sequence Info: Full Length of Mature Protein
MW: 42.5 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Major acute phase reactant. Apolipoprotein of the HDL complex.
Reference: Dog serum amyloid A protein. Identification of multiple isoforms defined by cDNA and protein analyses.Sellar G.C., Debeer M.C., Lelias J.M., Snyder P.W., Glickman L.T., Felsburg P.J., Whitehead A.S.J. Biol. Chem. 266:3505-3510(1991)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Major acute phase reactant. Apolipoprotein of the HDL complex.
Involvement in disease: Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Subcellular Location: Secreted
Protein Families: SAA family
Tissue Specificity: Expressed by the liver; secreted in plasma.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P19708
HGNC Database Link: N/A
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: N/A