Recombinant Dog Annexin A13 (ANXA13) | CSB-MP001839DO

Recombinant Dog Annexin A13 (ANXA13) | CSB-MP001839DO | Cusabio

Alternative Name(s): Annexin XIII Annexin-13 Intestine-specific annexin Short name: ISA

Gene Names: ANXA13

Research Areas: Signal Transduction

Organism: Canis lupus familiaris (Dog) (Canis familiaris)

AA Sequence: GNRHAKAKSHHGFDVDHDAKKLNKACKGMGTDEAAIIEILSSRTSDERQQIKQKYKATYGKDLEEVFKSDLSGNFEKTALALLDRPSEYDARQLQKAMKGLGTDEAVLIEILCTRTNKEIMAIKEAYQRLFDRSLESDVKADTSGNLKAILVSLLQANRDEGDDVDKDLAGQDAKDLYDAGDGRWGTDELAFNEVLAKRSHKQLRATFQAYQILIDKDIEEAIEAETSGDLQKAYLTLVRCARDQEGYFADRLYKSMKGTGTDEETLIHIIVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFQKLLVALLH

Source: Mammalian cell

Tag Info: N-terminal 6xHis-tagged

Expression Region: 2-316aa

Sequence Info: Full Length of Mature Protein

MW: 39.3 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Involved in vesicular traffic to the apical plasma membrane (isoform B).

Reference: "Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane."Fiedler K., Lafont F., Parton R.G., Simons K.J. Cell Biol. 128:1043-1053(1995).

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Involved in vesicular traffic to the apical plasma membrane (isoform B).

Involvement in disease:

Subcellular Location: Isoform B: Cytoplasmic vesicle

Protein Families: Annexin family

Tissue Specificity: Epithelia (isoform A); intestine and kidney (isoform B).

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q29471

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A