RBPJ Antibody, HRP conjugated | CSB-PA019486LB01HU

RBPJ Antibody, HRP conjugated | CSB-PA019486LB01HU | Cusabio

RBPJ Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: RBPJ

Aliases: Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30), RBPJ, IGKJRB IGKJRB1 RBPJK RBPSUH

Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q06330

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Recombining binding protein suppressor of hairless protein (243-485AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Stem cells