RBP4 Monoclonal Antibody | CSB-MA070501A0m

RBP4 Monoclonal Antibody | CSB-MA070501A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: RBP4

Aliases: Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222

Relevance: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP) , also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number: 6A1C2

Uniport ID: P02753

Alternatives To SCBT: sc-48384/sc-69795/sc-46688

Host Species: Mouse

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Retinol-binding protein 4 protein

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;Recommended dilution:WB:1:500-1:5000, IHC:1:50-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: IHC:1:50-1:500

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction