Rabbit anti-Mouse IgG Fc Antibody | CSB-PA00580E0Rb

Rabbit anti-Mouse IgG Fc Antibody | CSB-PA00580E0Rb | Cusabio

Rabbit anti-Mouse IgG Fc Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Secondary Antibody

Background: The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody’s two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6 linked sialic acid residues. The other part of an antibody, called the Fab region, contains variable sections that define the specific target that the antibody can bind. By contrast, the Fc region of all antibodies in a class are the same for each species; they are constant rather than variable. The Fc region is, therefore, sometimes incorrectly termed the "fragment constant region".

Isotype: IgG

Conjugate: Non-conjugated

Host Species: Rabbit

Species Reactivity: Mouse

Immunogen: Mouse IgG Fc fragment

Immunogen Species: Mouse

Applications: ELISA

Tested Applications: ELISA

Purification Method: Caprylic Acid Ammonium Sulfate Precipitation purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.