PTGS1 Antibody | CSB-PA164506

PTGS1 Antibody | CSB-PA164506 | Cusabio

PTGS1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PTGS1

Aliases: COX3; PCOX1; CYCLOOXYGENASE 1; PARTIAL COX1 PROTEINS; PGHS1 CYCLOOXYGENASE 3

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Lawrence M. Szewczuk, J. Biol. Chem., May 2004; 279: 22727 - 22737.
Syed R. Baber, Am J Physiol Heart Circ Physiol, Oct 2005; 289: H1476 - H1487.
Subhashini Chandrasekharan, J. Lipid Res., Dec 2005; 46: 2636 - 2648.
K. Trent Moreland, J. Pharmacol. Exp. T

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P23219

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from human COX1.

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cancer;Cardiovascular;Immunology;Metabolism;Signal transduction