PSENEN Antibody, HRP conjugated | CSB-PA878932OB01HU
- 3 to 7 Working Days
PSENEN Antibody, HRP conjugated | CSB-PA878932OB01HU | Cusabio
PSENEN Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: PSENEN
Aliases: Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2), PSENEN, PEN2
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111) . The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable) . PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111) .
Uniport ID: Q9NZ42
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Peptide sequence from Human Gamma-secretase subunit PEN-2 protein (39-57AA)
Immunogen Species: Homo sapiens (Human)
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Neuroscience