PRNP Antibody, FITC conjugated | CSB-PA018739LC01HU

PRNP Antibody, FITC conjugated | CSB-PA018739LC01HU | Cusabio

PRNP Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PRNP

Aliases: Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230), PRNP, ALTPRP PRIP PRP

Background: Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as a agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity) . Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu (2+) or ZN (2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity) .

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: P04156

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Major prion protein (23-64AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Stem cells