Prnp Antibody | CSB-PA018739LA01RA

Prnp Antibody | CSB-PA018739LA01RA | Cusabio

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Product Type: Polyclonal Antibody

Target Names: Prnp

Aliases: Major prion protein (PrP) (CD antigen CD230), Prnp, Prn Prp

Background: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) . Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu (2+) or ZN (2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P13852

Host Species: Rabbit

Species Reactivity: Rat

Immunogen: Recombinant Rat Major prion protein (29-231AA)

Immunogen Species: Rat

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others