PRF1 Antibody | CSB-PA018668LA01HU

PRF1 Antibody | CSB-PA018668LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: PRF1

Aliases: Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP), PRF1, PFP

Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P14222

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Perforin-1 protein (22-554AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology