PPARG Antibody | CSB-PA216430

PPARG Antibody | CSB-PA216430 | Cusabio

PPARG Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PPARG

Aliases: GLM1; NR1C3; PPARG1; PPARG2; PPARG

Background: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists."

Mukherjee R., Jow L., Croston G.E., et al. J. Biol. Chem. 272:8071-8076 (1997) "Cloning and characterization of RAP250, a nuclear receptor coactivator."
Caira F., Antonson P., Pelto-Huikko M., et al. J. Biol. Chem. 275:5308-5317 (2000) "Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor a."
Qi C., Chang J., Zhu Y., et al. J. Biol. Chem. 277:28624-28630 (2002) "

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P37231

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Peptide sequence around aa.50~54 (L-S-V-M-E) derived from Human PPARg

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

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Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cardiovascular;Metabolism;Stem cells