POMK Antibody, Biotin conjugated | CSB-PA863985LD01HU

POMK Antibody, Biotin conjugated | CSB-PA863985LD01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: POMK

Aliases: Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196), POMK, SGK196

Background: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc) -beta-1, 3-N-acetylglucosamine (GlcNAc) -beta-1, 4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1, 3-N-acetylglucosamine-beta-1, 4- (phosphate-6-) mannose) . Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9H5K3

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Protein O-mannose kinase protein (44-350AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction